Publications

In the following the most recent important publications of Prof. Hölscher et al are presented.
The complete list of publications with Original Papers can be found HERE as well as a list of book chapters HERE and books HERE.

The book Expertise Upper Gastrointestinal Tract in German language was published in March 2021 by Thieme Publishers.
It contains 404 pages and 502 figures and links to several videos of surgery of the esophagus and stomach

The abstracts of these publications can be found in the internet under PUBMED with the last name of the author, the initials and the year of appearance.

  • Dissecting the genetic heterogeneity of gastric cancer.

    Hess T, Maj C, Gehlen J, Borisov O, Haas SL, Gockel I, Vieth M, Piessen G, Hölscher AH et al
    eBioMedicine (Lancet Discovery Science)
    2023 Jun; 92: 104616
    Published free access online 2023 May 18
    doi: 10.1016/j.ebiom.2023.104616

  • Development and validation of a video-based procedure specific competency assessment tool for Minimal Invasive Esophagectomy.

    Ketel MHM, Klarenbeek BR, Eddahchouri Y, Cheong E, Cuesta M, van Daele E, Ferri LE, Gisbertz SS, Gutschow CA, Hubka M, Hölscher AH et al
    JAMA Surgery 2023 in press

  • Crowd-sourced and expert video assessment in minimally invasive esophagectomy.

    Ketel MHM, Klarenbeek BR, Eddahchouri Y, Cuesta MA, van Daele E, Gutschow CA, Hölscher AH, Hubka M, Luyer MDP, Merritt RE, Nieuwenhuijzen GAP, Shen Y, Abma IL, Rosman C, van Workum F
    Surg Endosc 2023 Oct,37(10): 7819-7828

  • Textbook oncological outcome in European Gastrodata.

    Sedlak K, Rawicz-Pruszynski K, Mlak R, van Sandick J, Gisbertz S, Pera M, dal Cero M, Baiocchi GL, Celotti A, Morgagni P, Vittimberga G, Hölscher AH, Polkowski WP
    Ann Surg 2023; Nov 278:823-831

  • Premature mortality for patients after completely resected early adenocarcinoma of the esophagus or stomach.

    Bollschweiler E, Plum P, Markar S, Alakus H, Drebber U, Mönig SP, Hölscher AH
    Cancer 2023 in press

  • Impact of the surgical approach for neoadjuvantly treated gastroesophageal junction type II tumors – a multi-national, high-volume center retrospective cohort analysis.

    Wirsik NM, Schmidt T, Nienhüser H, Donion NE, de Jongh C, Uzun E, Fuchs HF, Brunner S, Alakus H, Hölscher AH, Grimmiger P, Schneider M, Reynolds JV, van Hillegersberg R, Bruns CJ
    Ann Surg 2023; Nov 278(5):683-691

  • United European Gastroenterology Journal

    Porschen R, Fischbach W, Gockel I, Hollerbach S, Hölscher AH, Lynen Jansen P, Miehlke S, Pech O, Stahl M, Vanhoefer U, German Esophageal Cancer Guideline Commission, Ebert M
    2023 in press

  • An evaluation of international contemporary operative outcomes and management trends associated with esophagectomy: a four-year study of over 6000 patients using ECCG definitions and the online Esodata database.

    Kuppusamy MK, Low DE, Hölscher AH et al
    Ann Surg 2022; 275(3): 515-525

  • Development of a reliable surgical quality assurance system for 2-stage esophagectomy in randomized controlled trials.

    Harris A, Butterworth J, Bosnier PR, MacKenzie H, Tokunaga M, Hoelscher AH, Hanna GB et al
    Ann Surg 2022; 275(1): 121-130; DOI: 10.1097/SLA.0000000000003850

  • Short-term outcome of Ivor Lewis esophagectomy following neoadjuvant chemoradiation versus preoperative chemotherapy in patients with locally advanced adenocarcinoma of the esophagus and gastroesophageal junction: a propensity score-matched analysis.

    Plum PS, Damanakis A, Buschmann L, Ernst A, Datta RR, Schiffmann LM, Hölscher AH et al
    J Cancer Res Clin Oncol 2022; 148: 1223-1234

  • Does VO2 peak provide a prognostic value in esophagectomy and gastrectomy for post-operative outcomes?

    Niels T, Baltin CT, Kosanke G, Fetzner UK, Hoelscher AH, Bollschweiler E, Naendrup JH, Baumann FT
    In Vivo 2022; 36(4):1812-1819

  • GWAS meta-analysis of 16790 patients with Barrett`s oesophagus and esophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.

    Schröder J, Chegwidden L, Mai C, Gehlen J, Speller J, Böhmer AC, Borisov O, Hess T, Kreuser N, Venerito M, Hölscher AH et al
    Gut 2022; Jul 26; doi: 10.1136/gutjnl-2021-326698 online

  • eQTL set-based association analysis identifies novel susceptibility loci for Barrett esophagus and esophageal adenocarcinoma.

    Wang X, Gharahkhani P, Levine DM, Fitzgerald RC, Gockel I, Corley DA, Risch HA, Bernstein L, Chow W-H, Ostad L, Shaheen NJ, Lagergren J, Hölscher AH et al
    Cancer Epidemiol Biomarkers Prev 2022; 31(9): 1735-1745

  • Surgical approach to advanced Siewert II cancer: beyond the borders? The West side.

    Hölscher AH, Bollschweiler E, Fetzner UK, Babic B
    Updates Surg 2022 doi.org/10.1007/s13304-022-01363-w

  • The Effect of Postoperative Complications After Minimally Invasive Esophagectomy on Long-term Survival: An International Multicenter Cohort Study

    Fransen FC, Berkelmans, GHK, Asti E, Van Berge Henegouwen M, Berlth F, Hölscher AH
    Ann Surg 2021; 274(6): e1129-e1137
    DOI: 10.1097/SLA.0000000000003772

  • Patient, Surgeon, and Health Care Worker Safety during the COVID-19 Pandemic.

    Hölscher AH
    Ann Surg 2021; 274:681-687

  • Comment on `Is local endoscopic resection a viable therapeutic option for early clinical stage T1a and T1b esophageal adenocarcinoma? A propensity-matched analysis

    Hölscher AH, Bollschweiler E
    Ann Surg 2021; 274(6) e916-e917

  • Technique of open and minimally invasive intrathoracic reconstruction following esophagectomy – an expert consensus based on a modified Delphi process.

    Bartella I, Fransen LFC, Gutschow CA, Hölscher AH et al
    Dis Esophagus 2021; 34(11): doaa127

  • Germline variation in the insulin-like growth factor pathway and risk of Barrett`s esophagus and esophageal adenocarcinoma.

    Dighe SG, Chen J, Li Y, He Q, Gharahkhani P, Onstad L, Levine DM, Palles C, Hölscher AH et al
    Carcinogenesis 2021; 42(3):369-377

  • Risk prediction model of 90-day mortality after esophagectomy for cancer.

    D`Journo XB, Boulade D, Fourdrain A, Loundou A, van Berge Henegouwen MD, Gisbertz SS, O`Neill JR, Hoelscher AH et al
    JAMA Surgery 2021

  • Meta-analysis of randomized controlled trials and individual patient data comparing minimally invasive with open oesophagectomy for cancer.

    Müller-Stich BP, Probst P, Nienhüser H, Fazeli S, Senft J, Kalium E, Heger P, Hölscher AH et al
    Br J Surg 2021; 108(9): 1026-1033

  • Pretherapeutic misclassifications of esophageal cancer and adenocarcinoma of the esophagogastric junction. Possibilities and clinical consequences.

    Chirurg 2020; 91:41-50
    Gockel I, Lordick F, Lyros O, Kreuser N, Hölscher AH, Wittekind C

  • Esophagogastric junction adenocarcinomas – individualization of resection with special considerations for Siewert type II and Nishi types EG, E=G, and GE cancers.

    Gastric Cancer 2020; 23(1), 3-9
    Corrections: Gastric Cancer 2020; 23(1), 10
    Hölscher AH, Law S

  • Shared Genetic Etiology of Obesity-Related Traits and Barrett’s Esophagus/Adenocarcinoma: Insights From Genome-Wide Association Studies

    Cancer Epidemiol Biomarkers Prev
    2020; 29(2):427-433
    Böhmer AC, Hecker J, Schröder J, Gharahkhani P, May A, Hölscher AH

  • External Validation of Pretreatment Pathological Tumor Extent in Patients With Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer

    Ann Surg Oncol 2020; 27(4):1250-1258
    Brinkmann S, Noordman B, Hölscher AH et al

  • Neoadjuvant chemoradiation changes podoplanin expression in esophageal cancer patients

    Warnecke-Eberz U, Plum P, Drebber U, Hölscher AH, Bollschweiler E
    World J Gastroenterology 2020; 26(22): 0-0
    DOI: 10.3748/wjg.v26i22.0000

  • Different response rates to chemotherapy between Japanese and German ESCC-patients may be influenced by ERCC1 or ABCB1.

    Narumiya K, Bollschweiler E, Hölscher A H, Yamamoto M, Drebber U, Alakus H, Metzger R, Warnecke-Ebers U
    Future Oncology 2020 (in press)

  • Presidential Address:  European Surgical Association (ESA) during the COVID-19 time.

    Hölscher A H
    Ann Surg 2020 November 272(5):677

  • Propensity score-matched comparison between open and minimal invasive hybrid esophagectomy for esophageal adenocarcinoma.

    Hölscher AH, DeMeester TR, Schmidt H, Berlth F, Bollschweiler E
    Langenbecks Arch Surg  2020; 405 (4): 521-532

  • Sex-specific genetic associations for Barrett`s esophagus and esophageal adenocarcinoma.

    Ding J, Maj C, Tsavachidis S, Ostrom QT, Gharahkhani P, Anderson LA, Hölscher AH et al
    Gastroenterology 2020; 159(6): 2065-2076

  • S3-Leitlinie Diagnostik und Therapie der Plattenepithelkarzinome und Adenokarzinome des Ösophagus.

    Z Gastroenterol 2019; 57(3):e120

    Porschen R, Fischbach W, Gockel I, Hollerbach S, Hölscher AH et al

  • Benchmarking complications associated with esophagectomy.

    Ann Surg 2019; 269(2):291-298
    Low DE, Kuppusamy MK, Alderson D, Cecconello I, Chang A, Darling G, Davies A,
    D‘Journo XB, Gisbertz SS, Griffin M, Hardwick R, Hölscher A H et al

  • Aktualisierte S3 -Leitlinie zum Ösophaguskarzinom und Ergänzungen aus chirurgischer Sicht.

    Chirurg 2019; 90(5):398-402
    Hölscher AH, Gockel I, Porschen R

  • Double Tract Rekonstruktion nach Resektion des gastroösophagealen Übergangs wegen AEG II und III Tumoren

    Zentralbl Cir 2019; 144:1-6
    Hölscher AH, Berlth F, Hemmerich M, Minot S, Schmidt H

  • Impact of extracapsular lymph node involvement after neoadjuvant
    chemo radiation therapy followed by surgery in carcinoma of the esophagus: A
    multicenter study.

    Ann Surg 2018; 268(6):1000-1007
    Depypere LP, Moons J, Mariette C, D´Journo XB, Thomas PA, Hölscher AH,
    Bollschweiler E, van Berge Henegouwen MI, Van Lanscho t JJB, Lerut TEMR, Nafteux

  • Total minimally invasive esophagectomy for esophageal adenocarcinoma reduces postoperative pain and pneumonia compared to hybrid seophagectomy.

    Surg Endosc 2018; 32(12):4957-4965
    Berlth F, Plum PS, Chon SH, Gutschow CA, Bollschweiler E, Hölscher A H

  • Neoadjuvant chemotherapy or chemoradiation for
    patients with advanced adenocarcinoma oft the esophagus? A propensity score
    matched study.

    Eur J Surg Oncol; 2017 Aug; 43(8): 1572-1580
    Favi F, Bollschweiler E, Berlth F, Plum P, Hescheler DA, Alakus H, Semrau R, Celik E,
    Mönig SP, Drebber U, Hölscher AH

  • Current and future treatment options for esophageal cancer in the elderly.

    Expert Opin Pharmacother; 2017 Jul; 18(10): 1001-1010
    Bollschweiler E, Plum P, Mönig SP, Hölscher AH

  • Defining Benchmarks for transthoracic esophagectomy. A multicenter analysis of total minimal invasive esophagegtomy in low risk patients.

    Annals of Surgery; 2017:266 (5) 814-821
    Schmidt, HM, Gisbertz S, Moons J, Rouvelas I, Kauppi J, Brown A, Asti E, Luyer M, Lagarde S, Berlth F, Philippron A, Bruns C, Hölscher AH, Schneider P, Raptis D, van Berge Henegouven M, Nafteux P, Nilsson M, Räsanen J, Palazzo F, Rosato E, Mercer S, Bonavina L, Nieuwenhuijzen G, Wijnhoven B, Schröder W, Pattyn Piet, Grimminger P, Gutschow C

  • Ratgeber Ösophaguskarzinom

    Gastro Liga, Januar 2017
    Hölscher AH