Dissecting the genetic heterogeneity of gastric cancer.

Hess T, Maj C, Gehlen J, Borisov O, Haas SL, Gockel I, Vieth M, Piessen G, Hölscher AH et al
eBioMedicine (Lancet Discovery Science)
2023 Jun; 92: 104616
Published free access online 2023 May 18
doi: 10.1016/j.ebiom.2023.104616

Development and validation of a video-based procedure specific competency assessment tool for Minimal Invasive Esophagectomy.

Ketel MHM, Klarenbeek BR, Eddahchouri Y, Cheong E, Cuesta M, van Daele E, Ferri LE, Gisbertz SS, Gutschow CA, Hubka M, Hölscher AH et al
JAMA Surgery 2023 in press

Crowd-sourced and expert video assessment in minimally invasive esophagectomy.

Ketel MHM, Klarenbeek BR, Eddahchouri Y, Cuesta MA, van Daele E, Gutschow CA, Hölscher AH, Hubka M, Luyer MDP, Merritt RE, Nieuwenhuijzen GAP, Shen Y, Abma IL, Rosman C, van Workum F
Surg Endosc 2023 Oct,37(10): 7819-7828

Textbook oncological outcome in European Gastrodata.

Sedlak K, Rawicz-Pruszynski K, Mlak R, van Sandick J, Gisbertz S, Pera M, dal Cero M, Baiocchi GL, Celotti A, Morgagni P, Vittimberga G, Hölscher AH, Polkowski WP
Ann Surg 2023; Nov 278:823-831

Premature mortality for patients after completely resected early adenocarcinoma of the esophagus or stomach.

Bollschweiler E, Plum P, Markar S, Alakus H, Drebber U, Mönig SP, Hölscher AH
Cancer 2023 in press

Impact of the surgical approach for neoadjuvantly treated gastroesophageal junction type II tumors – a multi-national, high-volume center retrospective cohort analysis.

Wirsik NM, Schmidt T, Nienhüser H, Donion NE, de Jongh C, Uzun E, Fuchs HF, Brunner S, Alakus H, Hölscher AH, Grimmiger P, Schneider M, Reynolds JV, van Hillegersberg R, Bruns CJ
Ann Surg 2023; Nov 278(5):683-691

United European Gastroenterology Journal

Porschen R, Fischbach W, Gockel I, Hollerbach S, Hölscher AH, Lynen Jansen P, Miehlke S, Pech O, Stahl M, Vanhoefer U, German Esophageal Cancer Guideline Commission, Ebert M
2023 in press

An evaluation of international contemporary operative outcomes and management trends associated with esophagectomy: a four-year study of over 6000 patients using ECCG definitions and the online Esodata database.

Kuppusamy MK, Low DE, Hölscher AH et al
Ann Surg 2022; 275(3): 515-525

Development of a reliable surgical quality assurance system for 2-stage esophagectomy in randomized controlled trials.

651. Harris A, Butterworth J, Bosnier PR, MacKenzie H, Tokunaga M, Hoelscher AH, Hanna GB et al
Ann Surg 2022; 275(1): 121-130; DOI: 10.1097/SLA.0000000000003850

Short-term outcome of Ivor Lewis esophagectomy following neoadjuvant chemoradiation versus preoperative chemotherapy in patients with locally advanced adenocarcinoma of the esophagus and gastroesophageal junction: a propensity score-matched analysis.

Plum PS, Damanakis A, Buschmann L, Ernst A, Datta RR, Schiffmann LM, Hölscher AH et al
J Cancer Res Clin Oncol 2022; 148: 1223-1234

Does VO2 peak provide a prognostic value in esophagectomy and gastrectomy for post-operative outcomes?

Niels T, Baltin CT, Kosanke G, Fetzner UK, Hoelscher AH, Bollschweiler E, Naendrup JH, Baumann FT
In Vivo 2022; 36(4):1812-1819

GWAS meta-analysis of 16790 patients with Barrett`s oesophagus and esophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.

Schröder J, Chegwidden L, Mai C, Gehlen J, Speller J, Böhmer AC, Borisov O, Hess T, Kreuser N, Venerito M, Hölscher AH et al
Gut 2022; Jul 26; doi: 10.1136/gutjnl-2021-326698 online

eQTL set-based association analysis identifies novel susceptibility loci for Barrett esophagus and esophageal adenocarcinoma.

Wang X, Gharahkhani P, Levine DM, Fitzgerald RC, Gockel I, Corley DA, Risch HA, Bernstein L, Chow W-H, Ostad L, Shaheen NJ, Lagergren J, Hölscher AH et al
Cancer Epidemiol Biomarkers Prev 2022; 31(9): 1735-1745

Surgical approach to advanced Siewert II cancer: beyond the borders? The West side.

Hölscher AH, Bollschweiler E, Fetzner UK, Babic B
Updates Surg 2022 doi.org/10.1007/s13304-022-01363-w

The Effect of Postoperative Complications After Minimally Invasive Esophagectomy on Long-term Survival: An International Multicenter Cohort Study

Patient, Surgeon, and Health Care Worker Safety during the COVID-19 Pandemic.

Comment on `Is local endoscopic resection a viable therapeutic option for early clinical stage T1a and T1b esophageal adenocarcinoma? A propensity-matched analysis

Technique of open and minimally invasive intrathoracic reconstruction following esophagectomy – an expert consensus based on a modified Delphi process.

Germline variation in the insulin-like growth factor pathway and risk of Barrett`s esophagus and esophageal adenocarcinoma.

Risk prediction model of 90-day mortality after esophagectomy for cancer.

Meta-analysis of randomized controlled trials and individual patient data comparing minimally invasive with open oesophagectomy for cancer.

Prätherapeutische Fehlklassifikationen bei Ösophaguskarzinomen und Adenokarzinomen des ösophagogastralen Übergangs – Möglichkeiten und klinische Konsequenzen

Chirurg 2020; 91:41-50
Gockel I, Lordick F, Lyros O, Kreuser N, Hölscher AH, Wittekind C

Esophagogastric junction adenocarcinomas – individualisation of resection with special considerations for Siewert type II and Nishi types EG, E=G and GE cancers.

Gastric Cancer 2020; 23(1), 3-9
Corrections: Gastric Cancer 2020; 23(1), 10
Hölscher AH, Law S

Shared Genetic Etiology of Obesity-Related Traits and Barrett’s Esophagus/Adenocarcinoma: Insights From Genome-Wide Association Studies

Cancer Epidemiol Biomarkers
Prev2020; 29(2):427-433
Böhmer AC, Hecker J, Schröder J, Gharahkhani P, May A, Hölscher AH

External Validation of Pretreatment Pathological Tumor Extent in Patients With Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer

Ann Surg Oncol 2020; 27(4):1250-1258
Brinkmann S, Noordman B, Hölscher AH et al

Neoadjuvant chemoradiation changes podoplanin expression in esophageal cancer patients

Warnecke-Eberz U, Plum P, Drebber U, Hölscher AH, Bollschweiler E
World J Gastroenterology 2020; 26(22): 0-0
DOI: 10.3748/wjg.v26i22.0000

Different response rates to chemotherapy between Japanese and German ESCC-patients may be influenced by ERCC1 or ABCB1.

Narumiya K, Bollschweiler E, Hölscher A H, Yamamoto M, Drebber U, Alakus H, Metzger R, Warnecke-Ebers U
Future Oncology 2020 (in press)

Presidential Address:  European Surgical Association (ESA) during the COVID-19 time.

Hölscher A H
Ann Surg 2020 November 272(5):677

Propensity score-matched comparison between open and minimal invasive hybrid esophagectomy for esophageal adenocarcinoma.

Hölscher AH, DeMeester TR, Schmidt H, Berlth F, Bollschweiler E
Langenbecks Arch Surg  2020; 405 (4): 521-532

Sex-specific genetic associations for Barrett`s esophagus and esophageal adenocarcinoma.

Ding J, Maj C, Tsavachidis S, Ostrom QT, Gharahkhani P, Anderson LA, Hölscher AH et al
Gastroenterology 2020; 159(6): 2065-2076

S3-Leitlinie Diagnostik und Therapie der Plattenepithelkarzinome und Adenokarzinome des Ösophagus.

Z Gastroenterol 2019; 57(3):e120

Porschen R, Fischbach W, Gockel I, Hollerbach S, Hölscher AH et al

Benchmarking complications associated with esophagectomy.

Ann Surg 2019; 269(2):291-298
Low DE, Kuppusamy MK, Alderson D, Cecconello I, Chang A, Darling G, Davies A,
D‘Journo XB, Gisbertz SS, Griffin M, Hardwick R, Hölscher A H et al

Aktualisierte S3 -Leitlinie zum Ösophaguskarzinom und Ergänzungen aus chirurgischer Sicht.

Chirurg 2019; 90(5):398-402
Hölscher AH, Gockel I, Porschen R

Double Tract Rekonstruktion nach Resektion des gastroösophagealen Übergangs wegen AEG II und III Tumoren

Zentralbl Cir 2019; 144:1-6
Hölscher AH, Berlth F, Hemmerich M, Minot S, Schmidt H

PDF-Datei der wissenschaftlichen Datei

Impact of extracapsular lymph node involvement after neoadjuvant
chemo radiation therapy followed by surgery in carcinoma of the esophagus: A
multicenter study.

Ann Surg 2018; 268(6):1000-1007
Depypere LP, Moons J, Mariette C, D´Journo XB, Thomas PA, Hölscher AH,
Bollschweiler E, van Berge Henegouwen MI, Van Lanscho t JJB, Lerut TEMR, Nafteux

Total minimally invasive esophagectomy for esophageal adenocarcinoma reduces postoperative pain and pneumonia compared to hybrid seophagectomy.

Surg Endosc 2018; 32(12):4957-4965
Berlth F, Plum PS, Chon SH, Gutschow CA, Bollschweiler E, Hölscher A H

Neoadjuvant chemotherapy or chemoradiation for
patients with advanced adenocarcinoma oft the esophagus? A propensity score
matched study.

Eur J Surg Oncol; 2017 Aug; 43(8): 1572-1580
Favi F, Bollschweiler E, Berlth F, Plum P, Hescheler DA, Alakus H, Semrau R, Celik E,
Mönig SP, Drebber U, Hölscher AH

Current and future treatment options for esophageal cancer in the elderly.

Expert Opin Pharmacother; 2017 Jul; 18(10): 1001-1010
Bollschweiler E, Plum P, Mönig SP, Hölscher AH

Defining Benchmarks for transthoracic esophagectomy. A multicenter analysis of total minimal invasive esophagegtomy in low risk patients.

Annals of Surgery; 2017:266 (5) 814-821
Schmidt, HM, Gisbertz S, Moons J, Rouvelas I, Kauppi J, Brown A, Asti E, Luyer M, Lagarde S, Berlth F, Philippron A, Bruns C, Hölscher AH, Schneider P, Raptis D, van Berge Henegouven M, Nafteux P, Nilsson M, Räsanen J, Palazzo F, Rosato E, Mercer S, Bonavina L, Nieuwenhuijzen G, Wijnhoven B, Schröder W, Pattyn Piet, Grimminger P, Gutschow C

Ratgeber Ösophaguskarzinom

Gastro Liga, Januar 2017
Hölscher AH